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KMID : 1130220220260040363
Annals of Geriatric Medicine and Research
2022 Volume.26 No. 4 p.363 ~ p.366
A Case of Ralstonia pickettii Bloodstream Infection and the Growing Problem of Healthcare Associated Infections in Frail Older Adults
Fiore Francesca

Cacciatore Stefano
Elmi Daniele
Landi Francesco
Tupputi Salvatore
Agostino Clara
Montenero Rossella
Spaziani Giovanni
Medei Martina
Antocicco Manuela
Mammarella Federica
Taddei Eleonora
Gravina-Ester Manes
Bernabei Roberto
Abstract
Frailty is a clinically measurable state of vulnerability to developing increased dependency and/or mortality when exposed to a stressor. Chronic diseases, aggressive treatments, antibiotic overuse, microbiota changes, immune senescence, and increased use of medical devices and implants (i.e., central lines and catheters) expose modern patients to healthcare-associated infections (HAIs), multidrug-resistant bacteria, and new and unusual opportunistic pathogens. Older adults are among the main victims of HAIs and are associated with high costs, disability, morbidity, and mortality. Ralstonia pickettii is an emerging opportunistic pathogen that causes rare nosocomial infections in frail individuals. Herein, we present a case of bloodstream infection caused by R. pickettii in an 88-year-old woman with a relatively mild course. In addition to describing this unusual finding, this report discusses the problem of HAIs in older adults. Older age, comorbidities, and hospital admissions were among the main risk factors for HAIs. Adherence to guidelines, training, auditing, and surveillance is crucial for reducing the burden of HAIs in acute settings. Furthermore, avoiding incongruous hospitalizations would have positive implications both for preventing HAIs and improving patient quality of life.
KEYWORD
Ralstonia pickettii, Cross infection, Frailty, Aged
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